Mitomycin C is used as a chemotherapeutic agent due to its antitumor activity. It is used to treat upper gastro-intestinal cancers. It serves as an antineoplastic agent which inhibits DNA synthesis and induces apoptosis.
NWIBSHFKIJFRCO-WUDYKRTCSA-N. PubChem CID. 5746. ChEBI. CHEBI:27504. SMILES. CC1= C ( C (=O)C2= C (C1=O)N3CC4C (C3 (C2COC (=O)N)OC)N4)N. Catalog No. AAJ63193MA. Mfr: Alfa Aesar.
50-07-7 – Mitomycin C, 5 mg/ml in DMSO, sterile-filtered – J67460 – Alfa Aesar. Life Science. Cellular & Molecular Biology. Antibiotics.
Store at: 2-8°C. Antineoplastic antibiotic that acts as an alkylating agent after activation. Mitomycin C supresses the synthesis of nucleic acids and inhibits DNA synthesis. Mitomycin C can inhibit both gram positive and negative bacteria and acid-fact bacilli. A cell-cylce non specific agent, most active in the late G1 and early S phases.
Mitomycin C is an anti-neoplastic antibiotic, DNA inter-strand, cross-linking, alkylating agent that targets guanine nucleoside in the sequence 5?CpG-3?. It produces oxygen radicals and is preferentially toxic to hypoxic cells.
Alfa Aesar – Fisher Sci, Alfa Aesar – Wikipedia, Alfa Aesar, Mitomycin C [ CAS# 50-07-7 ] The SDS samples above are collected from the Internet by chemBlink and displayed here for the tutorial purpose only. chemBlink Inc. provides the information contained herein.
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It is used to lubricate synthetic and silicone rubber gaskets. Further, it is used to lubricate plug valves, control valves, flow meter bearings, ceramic plug cocks and fire extinguisher valves. Pricing and Availability. Diethyl ether, >99%, inhibitor free, Alfa Aesar ™.
Originally based in Lancaster, it quickly grew, moving to a purpose built location at Heysham following a serious fire at its second location on Caton Road, Lancaster. It was subsequently sold to Johnson-Matthey for £25,000,000[8]and integrated into Alfa – Aesar , becoming their main organic production plant.
